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An economic analysis of Native CHOICES.

Robert Rosenman1, Carolyn Noonan2, Richard F MacLehose3

  • 1School of Economic Sciences, Washington State University, Pullman, WA, 99163, USA.

Journal of Substance Use and Addiction Treatment
|December 22, 2025
PubMed
Summary

Native CHOICES is a cost-effective program that reduces alcohol-exposed pregnancies (AEPs) and fetal alcohol spectrum disorders (FASDs) in American Indian communities. The intervention demonstrates significant economic benefits and improved quality of life.

Keywords:
Alcohol exposed pregnanciesCost benefitCost efficiencyFetal alcohol spectrum disorders

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Area of Science:

  • Public Health
  • Health Economics
  • Preventive Medicine

Background:

  • Fetal alcohol spectrum disorders (FASDs) are a significant public health concern linked to alcohol-exposed pregnancies (AEPs).
  • The Native CHOICES program, a culturally adapted intervention, effectively reduces AEP risk in American Indian communities.
  • This study provides the first economic analysis of the Native CHOICES program.

Purpose of the Study:

  • To conduct an economic analysis of the Native CHOICES program.
  • To assess the cost-benefit, cost-effectiveness, and quality-adjusted life years (QALYs) gained from Native CHOICES.
  • To evaluate the program's impact on reducing AEPs and FASDs.

Main Methods:

  • Utilized pre-pandemic data from a randomized controlled trial of Native CHOICES.
  • Conducted economic assessments including cost-benefit, cost-effectiveness, and QALY analysis.
  • Focused on a Northern Plains American Indian community.

Main Results:

  • Native CHOICES reduced AEP risk by 18-20% and FASDs by 6.84-7.6% within 6 months post-participation.
  • The program yielded a net economic benefit of $308,295 to $376,951 over 6 months.
  • Cost efficiency for FASDs avoided ranged from $84,887 to $93,709, with $2330-$2572 per QALY gained.

Conclusions:

  • Native CHOICES is a cost-effective intervention for preventing AEPs and FASDs.
  • The program demonstrates positive economic returns and improved health outcomes for American Indian participants.
  • Culturally adapted public health programs can be both effective and economically viable.