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Topological Feature Extraction from Multi-color Channels for Pattern Recognition: An Application to Fundus Image
Fatih Gelir1, Taymaz Akan1, Owen T Carmichael2
1Division of Clinical Informatics, Department of Internal Medicine, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA, 71103, USA.
Journal of Imaging Informatics in Medicine
|December 22, 2025
Summary
This study introduces color-based topological features combined with deep learning for enhanced medical image analysis and disease detection. These novel features significantly improve diagnostic accuracy in ophthalmology.
Area of Science:
- Medical Imaging Analysis
- Computer Vision
- Artificial Intelligence in Healthcare
Background:
- Automated medical image analysis is vital for early disease detection.
- Deep learning models have shown significant promise in analyzing complex medical images.
- Understanding image topology and color variations can reveal crucial diagnostic information.
Purpose of the Study:
- To explore the efficacy of color-based topological features for pattern recognition in medical images.
- To integrate topological, Local Binary Pattern (LBP), and Gabor features with deep learning for disease classification.
- To evaluate the performance of these models on diverse public fundus image datasets.
Main Methods:
- Extraction of topological features across different color channels to capture shape and connectivity.
- Integration of topological, LBP, and Gabor features.
- Application of machine learning and deep learning models for classification tasks.
- Validation using three large-scale fundus image datasets (APTOS 2019, ORIGA, ICHALLENGE-AMD).
Main Results:
- Color-based topological features provide significant information for disease diagnosis.
- The combined feature approach demonstrated strong performance in classifying retinal diseases.
- The study highlights the importance of color space in topological feature extraction for medical imaging.
Conclusions:
- Color-based topological features are valuable for automated medical image analysis.
- Deep learning models augmented with these features enhance disease detection capabilities.
- This approach offers a promising direction for improving diagnostic accuracy in ophthalmology.
Keywords:
Convolutional neural networkDeep learningPattern recognitionPersistent homologyTopological feature
