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Updated: Jan 8, 2026
Measuring the Behavioral Effects of Intraocular Scatter
Published on: February 18, 2021
Quantifying glare phenomena in patients with different intraocular lenses using a standard and modified clinical
Tadas Naujokaitis1, Asu Rayamajhi, Gerd U Auffarth
1From the International Vision Correction Research Center and the David J. Apple Center for Vision Research, Department of Ophthalmology, University of Heidelberg, Heidelberg, Germany (Naujokaitis, Rayamajhi, Auffarth, Khoramnia, Łabuz); Department of Ophthalmology, Faculty of Medicine and University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany (Naujokaitis, Khoramnia); Light Technology Institute, Karlsruhe Institute of Technology, Karlsruhe, Germany (Rayamajhi); Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, the Netherlands (van den Berg).
Purpose:
To assess whether differences in straylight can be detected in patients implanted with multifocal intraocular lenses (IOLs) using a standard and modified clinical straylight measurement.
Setting:
Tertiary care university eye clinic.
Design:
Comparative cross-sectional study.
Methods:
Straylight was measured at 7 and 2.5 degrees using the standard and modified C-Quant devices. 2 measurements per eye and angle were obtained. Logarithm of the straylight parameter (s) at both angles and its increase between 7 and 2.5 degrees were compared between study groups.
Results:
38 patients (67 eyes) were included in total: 12 patients (24 eyes) implanted with Tecnis Synergy, 13 patients (25 eyes) with Clareon PanOptix, and 13 patients (18 eyes) with monofocal lenses. The mean (±SD) straylight values at 7 degrees were 0.98 ± 0.16 log(s) with Synergy, 1.03 ± 0.14 log(s) with PanOptix, and 1.05 ± 0.22 log(s) with monofocal controls ( P = .864). At 2.5 degrees, they were 1.55 ± 0.09 log(s) with Synergy, 1.34 ± 0.10 log(s) with PanOptix, and 1.29 ± 0.21 log(s) with monofocal IOLs ( P < .001). The increase in straylight at 2.5 degrees was 0.57 ± 0.13 log(s) for Synergy, 0.31 ± 0.11 log(s) for PanOptix, and 0.25 ± 0.10 log(s) for monofocal controls ( P < .001).
Conclusions:
Straylight measurements at 2.5 degrees using the modified technique showed higher straylight levels with Synergy when compared with PanOptix and monofocal IOLs, whereas the standard technique did not detect differences between IOLs. Straylight testing at smaller angles emerges as a sensitive measure to identify multifocal designs posing an increased risk of inducing photic phenomena in pseudophakic patients.
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