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Updated: Jan 8, 2026

Adjustable Stiffness, External Fixator for the Rat Femur Osteotomy and Segmental Bone Defect Models
Published on: October 9, 2014
Evolution trends internal fixation materials knowledge mapping
Xiaozhou Lin1,2, Qianqian Wu1,2, Mengzhen Shi1,2
1School of Medicine, Qinghai University, Xining, Qinghai, China.
Bibliometric analysis reveals key trends in internal fixation materials (IFM) for orthopedic fracture repair. Research is shifting towards biodegradable and bioactive materials to improve bone healing and biocompatibility.
Area of Science:
- Orthopedic biomaterials research
- Biomedical engineering
- Materials science
Background:
- Internal fixation materials (IFM) are vital for fracture fixation and bone healing in orthopedics.
- Traditional metallic IFM (stainless steel, titanium alloys) have limitations in biocompatibility.
- Recent focus is on biodegradable materials like magnesium alloys and composites for enhanced biocompatibility.
Purpose of the Study:
- To analyze research hotspots, trends, and dynamics in internal fixation materials (IFM) from 2004-2024.
- To identify key themes, influential researchers, and leading institutions in the IFM field.
- To provide insights into the evolution and future directions of IFM research.
Main Methods:
- Bibliometric analysis using VOSviewer and CiteSpace.
- Keyword co-occurrence and citation analysis of IFM research.
- Dataset available at https://github.com/Lin1Xiao2Zhou3/VOS-CiteSpace-Datasets and https://doi.org/10.5281/zenodo.14277420.
Main Results:
- Core research priorities include bioactive materials, mechanical properties, and biodegradability for bone healing.
- Emerging research directions involve novel materials, advanced composites, and biomedical engineering applications.
- Key themes identified are enhanced biocompatibility and reduced need for secondary surgeries.
Conclusions:
- The field of IFM is evolving towards advanced biodegradable and bioactive materials.
- Future research should focus on personalized designs and improved biocompatibility for clinical needs.
- This study offers a comprehensive overview for researchers in academia and clinical practice.
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07:41An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice
Published on: November 13, 2016
08:20A Reliable and Reproducible Critical-Sized Segmental Femoral Defect Model in Rats Stabilized with a Custom External Fixator
Published on: March 24, 2019
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