Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

443
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
443
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

360
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
360
REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

1.3K
REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
1.3K
Sleep-Wake Cycles01:24

Sleep-Wake Cycles

2.7K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
2.7K
Understanding Sleep01:11

Understanding Sleep

1.4K
Sleep, an essential biological state, involves significant reductions in physical activity, sensory awareness, and interaction with the environment. This complex physiological process is primarily regulated by specific brain regions, notably the hypothalamus and pons, which govern the sleep-wake cycle or circadian rhythm.
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
1.4K
Alterations in Respiration II01:30

Alterations in Respiration II

1.6K
There are numerous types of normal and abnormal respiration. Based on ventilatory movements, breathing patterns are classified as regular, deep, or shallow. Examples include Biot's breathing, Cheyne-Stokes respiration, Kussmaul's breathing, hyperventilation, and hypoventilation. Each pattern is clinically significant and aids in evaluating patients.
In Biot's breathing, the respiratory rate and depth are irregular, alternating between periods of deep gasping and apnea. Common causes...
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Machine learning reveals distinct temperature thresholds and environmental modulators for atopic dermatitis and allergic contact dermatitis prevalence in South Korea.

PloS one·2026
Same author

Spatial mapping of nasal polyp distribution in an ovalbumin and Staphylococcal enterotoxin B-induced murine model of chronic rhinosinusitis.

Clinical and experimental otorhinolaryngology·2026
Same author

Region-Resolved Proteomics Identifies Molecular Features at the Mucosa-Polyp Interface in Chronic Rhinosinusitis.

International forum of allergy & rhinology·2026
Same author

Non-contact on-device detection of obstructive sleep apnea from infrared video.

Nature communications·2026
Same author

A Chronic Psoriasis Model Using Long-Term Imiquimod Application in IL-10-Deficient Mice: Recapitulating Skin Inflammation, Comorbidities, and Gut-Skin Axis Alterations.

Annals of dermatology·2025
Same author

Treatment Persistence After Major Cardiovascular Events in Psoriasis: A Retrospective Cohort Study Comparing Biologic, Systemic, and Phototherapy.

The Journal of dermatology·2025

Related Experiment Video

Updated: Jan 8, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.4K

Refining Sleep-Disordered Breathing Annotations Across Multiple Public Sleep Study Datasets.

Hyun Keun Ahn1, Younghoon Na1,2, Hyun-Woo Shin1,2,3,4,5,6

  • 1Obstructive Upper Airway Research Laboratory (OUaR LaB), Department of Pharmacology, Seoul National University College of Medicine, Seoul, South Korea.

Journal of Sleep Research
|December 23, 2025
PubMed
Summary

A new standardized pipeline improves polysomnography annotation for sleep apnea research. This enhances accuracy in apnea-hypopnea index calculation and obstructive sleep apnea severity classification.

Keywords:
data annotationdata qualitydeep learningpolysomnographyquality improvementsleep‐disordered breathing

More Related Videos

Method to Obtain Pattern of Breathing in Senescent Mice through Unrestrained Barometric Plethysmography
09:13

Method to Obtain Pattern of Breathing in Senescent Mice through Unrestrained Barometric Plethysmography

Published on: April 28, 2020

7.0K
Multi-Modal Home Sleep Monitoring in Older Adults
07:40

Multi-Modal Home Sleep Monitoring in Older Adults

Published on: January 26, 2019

8.1K

Related Experiment Videos

Last Updated: Jan 8, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.4K
Method to Obtain Pattern of Breathing in Senescent Mice through Unrestrained Barometric Plethysmography
09:13

Method to Obtain Pattern of Breathing in Senescent Mice through Unrestrained Barometric Plethysmography

Published on: April 28, 2020

7.0K
Multi-Modal Home Sleep Monitoring in Older Adults
07:40

Multi-Modal Home Sleep Monitoring in Older Adults

Published on: January 26, 2019

8.1K

Area of Science:

  • Sleep Medicine
  • Biomedical Data Science
  • Artificial Intelligence in Healthcare

Background:

  • Existing polysomnography annotations in major sleep studies (SHHS, MrOS, MESA) used simplified criteria for apneas/hypopneas, deviating from American Academy of Sleep Medicine (AASM) guidelines.
  • This inconsistency leads to inaccurate apnea-hypopnea indices (AHIs) and potentially flawed research conclusions.

Purpose of the Study:

  • To develop and validate a standardized annotation pipeline for polysomnography data integrating sleep staging, oxygen desaturation, and arousal events per AASM criteria.
  • To re-evaluate AHI and obstructive sleep apnea (OSA) severity in large cohorts using refined annotations.
  • To assess the impact of improved annotations on deep learning model performance for OSA classification.

Main Methods:

  • Developed a standardized annotation pipeline incorporating AASM guidelines for sleep staging, oxygen desaturation, and arousal events.
  • Retrospectively analyzed polysomnography data from SHHS1, SHHS2, MrOS1, MrOS2, MESA, and KISS cohorts.
  • Compared original AHI values with recalculated AHIs using the refined pipeline and trained deep learning models on both original and refined annotations.

Main Results:

  • Original annotations in SHHS, MrOS, and MESA significantly overestimated AHIs (MAE: 10.3–23.6 events/h).
  • Refined annotations drastically reduced MAE to 0.56–1.29 events/h, demonstrating improved accuracy.
  • Deep learning model performance for OSA severity classification improved, with the F1 score increasing from 0.5 to 0.69 after annotation refinement.

Conclusions:

  • The standardized annotation pipeline enhances cross-cohort consistency and accuracy in polysomnography analysis.
  • This approach enables more reliable utilization of existing sleep study datasets for clinical research and AI-driven applications.
  • Adherence to AASM guidelines through standardized annotation is crucial for accurate sleep apnea assessment and research.