Accelerating evidence generation to implementation: Establishment of the Leading Awareness to Action through

Laney K Jones1, Ty J Gluckman2, Ankeet S Bhatt3,4

  • 1Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA, USA.

Insights

The Leading Awareness to Action through Implementation of Cardiometabolic Efforts (LATTICE™) consortium accelerates the adoption of new cardiometabolic therapies. This initiative bridges the gap between evidence and practice to improve patient outcomes and reduce mortality.

Area of Science:

  • Cardiology
  • Metabolic Disorders
  • Implementation Science

Background:

  • Cardiovascular disease and metabolic disorders are leading causes of mortality globally.
  • Translating scientific advancements into clinical practice is often slow, limiting patient benefit.
  • The gap between evidence generation and healthcare implementation necessitates scalable solutions.

Purpose of the Study:

  • To establish the Leading Awareness to Action through Implementation of Cardiometabolic Efforts (LATTICE™) consortium.
  • To create a collaborative platform for sharing evidence-based tools and strategies for cardiometabolic health.
  • To accelerate the implementation of innovative therapies to reduce cardiometabolic events.

Main Methods:

  • Exploring novel strategies for translating evidence-based advancements into diverse clinical settings.
  • Disseminating successful strategies through collaboration among stakeholders (clinicians, payors, patients, industry).
  • Prioritizing projects that rigorously test implementation science strategies for scalability.

Main Results:

  • The LATTICE consortium was established in 2023 to unite partners focused on improving cardiometabolic health.
  • The consortium facilitates the sharing of tools, methodologies, and strategies to address care gaps.
  • Focus on scalable and sustainable healthcare strategies for widespread adoption.

Conclusions:

  • The LATTICE consortium aims to improve awareness, access, and implementation of effective cardiometabolic care strategies.
  • Successful implementation will lead to reduced morbidity and mortality from cardiometabolic events.
  • Collaboration and implementation science are key to achieving population-level benefit in cardiometabolic health.