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Updated: Jan 8, 2026

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Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss
Published on: April 11, 2025
829
[Transient visual loss in morning glory syndrome]
N L Sheremet1, M H Durzhinskaya1, A A Kaloshina1
1Krasnov Research Institute of Eye Diseases, Moscow, Russia.
Vestnik Oftalmologii
|December 23, 2025
Summary
Transient visual loss (TVL) can be linked to rare optic disc anomalies. This case highlights morning glory syndrome (MGS) causing exertional TVL due to optic disc changes and vascular compromise.
Area of Science:
- Ophthalmology
- Neuro-ophthalmology
Background:
- Monocular transient visual loss (TVL) has diverse etiologies requiring thorough diagnostic evaluation.
- Rarely, TVL is associated with optic disc anomalies like morning glory syndrome (MGS), coloboma, or optic disc drusen.
Purpose of the Study:
- To present a clinical case of TVL in a patient diagnosed with MGS.
- To investigate the relationship between MGS and exertional TVL.
Main Methods:
- Clinical case presentation.
- Ophthalmoscopy to examine optic disc morphology and function.
- Ultrasonography to assess retrobulbar structures and vascular supply.
Main Results:
- A 25-year-old patient experienced recurrent TVL in the left eye, triggered by exertion and straining.
- Ophthalmoscopy revealed MGS with exercise-induced contractile movements of the optic disc during TVL episodes.
- Ultrasonography identified an avascular hyperechoic structure causing lateral displacement of the central retinal artery and vein.
Conclusions:
- MGS can be a cause of monocular TVL, particularly when associated with exertional optic disc movements.
- Vascular compromise due to structural anomalies within the optic disc appears to be the mechanism for TVL in this MGS case.
- The optic nerve changes causing TVL were localized and not indicative of systemic disease.
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