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Pregnancy-related acute kidney injury in south India: Clinical profile and maternal outcomes

Thotanolla Surya Prakash1, Namesh Kamat1, Jeeja Jaya Janardhanan1

  • 1Assistant Professor, Department of Nephrology, Sri Venkateswara Institute of Medical Sciences, Tirupati, India.

Tropical Doctor
|December 23, 2025
PubMed

Pregnancy-related acute kidney injury (PR-AKI) is an uncommon but serious complication that poses significant maternal and foetal risks. This retrospective study analysed 83 cases of PR-AKI to evaluate causes, clinical features, and outcomes. Overall, 71% recovered, 23% developed chronic kidney disease (CKD), and 6% died. Thrombotic microangiopathy carried the highest CKD risk (85%), while sepsis caused most deaths (27%). Patients who could be managed conservatively recovered fully, whereas those more severe illness requiring dialysis inevitably had less favourable outcomes. Early recognition of high-risk conditions and timely intervention can therefore improve renal recovery and maternal survival.

Keywords:
HELLP syndromePregnancy-related acute kidney injurypostpartum haemorrhagepre-eclampsiathrombotic microangiopathy

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