Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Dementia01:30

Dementia

482
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
482
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

744
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
744
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

1.6K
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
1.6K
Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

1.7K
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Digital Phenotyping via Passive Network Traffic Monitoring: Prospective Observational Study in University Students.

JMIR formative research·2026
Same author

Digital Phenotyping via Passive Network Traffic Monitoring: Prospective Observational Study in University Students.

JMIR formative research·2026
See all related articles

Related Experiment Video

Updated: Jan 8, 2026

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
07:31

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills

Published on: February 13, 2020

7.3K

Technology and Dementia Preconference.

Rameen Mahmood1, Danny Yuxing Huang1

  • 1New York University, Brooklyn, NY, USA.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 23, 2025
PubMed
Summary
This summary is machine-generated.

RouterSense passively monitors home network activity to detect digital biomarkers for early Alzheimer's disease and related dementias (ADRD) detection. This scalable, software-only solution offers a cost-effective alternative to current monitoring methods.

More Related Videos

The Immersive Cleveland Clinic Virtual Reality Shopping Platform for the Assessment of Instrumental Activities of Daily Living
08:36

The Immersive Cleveland Clinic Virtual Reality Shopping Platform for the Assessment of Instrumental Activities of Daily Living

Published on: July 28, 2022

4.3K
Transcranial Pulse Stimulation for Alzheimer's Patients
06:08

Transcranial Pulse Stimulation for Alzheimer's Patients

Published on: April 4, 2025

2.0K

Related Experiment Videos

Last Updated: Jan 8, 2026

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
07:31

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills

Published on: February 13, 2020

7.3K
The Immersive Cleveland Clinic Virtual Reality Shopping Platform for the Assessment of Instrumental Activities of Daily Living
08:36

The Immersive Cleveland Clinic Virtual Reality Shopping Platform for the Assessment of Instrumental Activities of Daily Living

Published on: July 28, 2022

4.3K
Transcranial Pulse Stimulation for Alzheimer's Patients
06:08

Transcranial Pulse Stimulation for Alzheimer's Patients

Published on: April 4, 2025

2.0K

Area of Science:

  • Digital Health
  • Biomarker Discovery
  • Neurodegenerative Disease Research

Background:

  • Alzheimer's disease and related dementias (ADRD) have a prolonged preclinical phase with subtle early indicators.
  • Existing monitoring solutions are often costly, intrusive, and require user compliance, limiting long-term feasibility.
  • There is a need for scalable, passive, and continuous monitoring for early ADRD detection.

Purpose of the Study:

  • To introduce RouterSense, a novel software-only tool for passive, continuous monitoring of digital biomarkers.
  • To evaluate RouterSense's capability in detecting behaviors associated with early ADRD.
  • To address the limitations of current ADRD monitoring approaches.

Main Methods:

  • RouterSense analyzes encrypted network activity from commodity hardware to establish baseline behaviors.
  • Machine learning algorithms detect deviations in sleep-wake cycles, app usage, and out-of-home activity.
  • A preliminary 72-hour study with 3 cognitively intact participants compared network data to self-reported logs.

Main Results:

  • RouterSense identified key digital biomarkers linked to ADRD, including disrupted sleep patterns (e.g., nighttime app usage).
  • Observed shifts in daily app engagement patterns, from work-related to entertainment, were detected.
  • Inferred out-of-home activity changes, a common indicator in ADRD, were identified through network analysis.

Conclusions:

  • RouterSense provides a scalable, passive solution for early ADRD detection using network traffic analysis.
  • The system overcomes limitations of existing methods by not requiring active user engagement or extra hardware.
  • Future research will focus on larger, longitudinal studies with ADRD populations and integrating real-time alerts.