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Public Health.

Joshua O Akinyemi1, Carolina Scaramutti2, Dingtian Cai3

  • 1College of Medicine, University of Ibadan, Ibadan, Oyo, Nigeria.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 23, 2025
PubMed
Summary
This summary is machine-generated.

Low social engagement (SE) increases Alzheimer's Disease (AD) risk in African adults. Promoting social participation may help reduce AD incidence in these populations.

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Area of Science:

  • Neuroscience
  • Public Health
  • Gerontology

Background:

  • Social engagement (SE) is a recognized modifiable risk factor for Alzheimer's Disease (AD).
  • Its influence among indigenous African populations remains under-explored.
  • Understanding SE's role is vital for targeted AD interventions in Africa.

Purpose of the Study:

  • To investigate the association between social engagement and Alzheimer's Disease (AD) risk.
  • To explore the impact of media consumption (radio, TV) on AD risk in African populations.

Main Methods:

  • A case-control study of 1,018 participants (509 AD cases, 509 controls) from nine African countries.
  • SE assessed via self-reported interaction frequency; media habits recorded.
  • Conditional logistic regression adjusted for demographic and socioeconomic factors.

Main Results:

  • Low adult SE was significantly associated with increased odds of AD (AOR=1.89).
  • Daily radio listening was linked to reduced AD odds (AOR=0.29).
  • Daily TV watching showed a trend towards reduced AD odds (OR=0.69).

Conclusions:

  • Low social engagement is a significant risk factor for AD in African populations.
  • Interventions promoting social inclusion and reducing isolation are recommended.
  • Further longitudinal research is needed to explore protective factors and mechanisms in diverse African contexts.