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Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
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Public Health.

Owen T Carmichael1, Angelique Litsey1, Neil Johannsen2

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|December 23, 2025
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Summary
This summary is machine-generated.

Higher aerobic fitness is linked to better cognitive function in older African Americans. This study highlights the importance of cardiorespiratory fitness for maintaining brain health in this demographic.

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Area of Science:

  • Gerontology
  • Exercise Science
  • Neuroscience

Background:

  • Physical activity and aerobic fitness interventions improve cognitive performance in older adults.
  • The role of aerobic fitness as a risk factor for cognitive decline in older African Americans is not well understood.
  • Previous studies lacked sufficient sample sizes of older African Americans.

Purpose of the Study:

  • To investigate the association between baseline aerobic fitness and cognitive function in older African Americans.
  • To examine aerobic fitness as a potential risk factor for cognitive impairment in this population.
  • To address the gap in research concerning aerobic fitness and cognition in older African Americans.

Main Methods:

  • The Reducing African Americans' Alzheimer's Disease Risk Through Exercise (RAATE) Study enrolled 129 sedentary, cognitively healthy older African Americans.
  • Participants were randomized to one year of aerobic exercise training or successful aging education.
  • Baseline aerobic fitness (peak VO2) was assessed using a graded sub-maximal treadmill test and related to cognitive scores via linear regression.

Main Results:

  • Greater peak VO2 was significantly associated with higher global cognitive scores (NIH Toolbox) and dimensional change card sort scores.
  • In men, greater peak VO2 was specifically linked to better pattern comparison processing.
  • No significant associations were found between peak VO2 and other cognitive measures.

Conclusions:

  • Increased aerobic fitness is associated with enhanced global cognitive function in healthy older African American adults.
  • Sex-specific associations between aerobic fitness and cognitive domains warrant further investigation in this population.
  • Aerobic fitness may play a crucial role in preserving cognitive function among older African Americans.