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Related Concept Videos

Primary Healthcare Services01:30

Primary Healthcare Services

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Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
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Levels of Health Promotion and Illness Prevention01:26

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Health promotion allows a person to control the determinants of health, resulting in an improved health status. It enhances the quality of life and reduces premature deaths. Health promotion and illness prevention programs help people make beneficial choices to reduce the risk of disease and disabilities. There are three health promotion and illness prevention levels: primary, secondary, and tertiary prevention.
In primary prevention, actions taken before disease onset prevent the disease from...
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Preventive Healthcare Services01:30

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Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
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Principles of Disease Surveillance01:26

Principles of Disease Surveillance

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Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
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Healthcare Agencies II01:17

Healthcare Agencies II

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There are various healthcare agencies in the United States—some of which are managed by religious institutions and others by different government branches.
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources,...
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Methods Of Healthcare Delivery System01:26

Methods Of Healthcare Delivery System

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At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
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Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
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Public Health.

Oshadi M Jayakody1, Ying Jin1, Daniel M Aharon1

  • 1Albert Einstein College of Medicine, Bronx, NY, USA.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 23, 2025
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Summary
This summary is machine-generated.

Recruitment for Alzheimer's disease clinical trials faces barriers like lack of interest and strict eligibility criteria. Addressing these can improve enrollment, especially for diverse older adults in ADRD research.

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Area of Science:

  • Gerontology
  • Clinical Trials
  • Neuroscience

Background:

  • Alzheimer's Disease and Related Dementias (ADRD) clinical trials face significant recruitment challenges, particularly with underrepresented populations.
  • These challenges lead to trial delays, increased costs, and reduced scientific validity.

Purpose of the Study:

  • To examine participant- and study-related barriers to recruitment in ADRD clinical trials.
  • To identify modifiable barriers for future recruitment strategies.

Main Methods:

  • Analysis of screen failure data from two ADRD clinical trials involving diverse older adults.
  • Systematic review and categorization of screen failure reasons by independent raters.
  • Statistical analysis to determine the influence of participant characteristics on screen failure likelihood.

Main Results:

  • Sixty-two percent of screen failures were participant-related (e.g., lack of interest, scheduling conflicts, illness).
  • Study-related reasons included ineligibility (57%), study burden (19%), and concurrent enrollment (14%).
  • Women reported more mistrust; minority older adults were disproportionately screen-failed due to eligibility criteria.

Conclusions:

  • Identified modifiable participant-related barriers include lack of awareness and need for trusted messengers.
  • Study-related strategies should involve reconsidering restrictive eligibility criteria and offering incentives.
  • Examining intersectionality of social identities is crucial for designing inclusive ADRD trials.