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Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
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Public Health.

Debora Melo van Lent1,2, Daniel Koijs3,4,5, Josh Bis6

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Summary
This summary is machine-generated.

Adhering to the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet is linked to a reduced risk of dementia. Higher MIND diet scores also increase the likelihood of remaining dementia-free at age 80.

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Area of Science:

  • Neuroscience
  • Nutritional Science
  • Epidemiology

Background:

  • Observational studies suggest a link between the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet and reduced dementia risk.
  • The MIND diet combines aspects of the Mediterranean and DASH diets, focusing on brain-healthy foods.

Purpose of the Study:

  • To investigate the association between MIND diet scores and the risk of incident all-cause dementia.
  • To examine the relationship between MIND diet scores and the probability of being alive and dementia-free at age 80.

Main Methods:

  • Analysis of data from 8,714 dementia-free adults across six community-based cohorts.
  • Utilized Cox and logistic regression models, with results combined via meta-analysis.
  • MIND diet scores were calculated based on ten healthy and five unhealthy dietary components.

Main Results:

  • Higher MIND diet scores were associated with a decreased risk of all-cause dementia (HR=0.96, 95% CI=0.93-0.99).
  • MIND diet scores of 6 or higher showed a significant reduction in dementia risk (HR=0.86, 95% CI=0.78-0.94).
  • Higher MIND diet scores correlated with increased odds of being alive and dementia-free at age 80 (OR=1.11, 95% CI=1.07-1.15).

Conclusions:

  • The MIND diet is associated with a reduced risk of all-cause dementia.
  • Higher adherence to the MIND diet is linked to a greater chance of remaining dementia-free at age 80.
  • Further clinical trials are recommended to explore a potential causal relationship between the MIND diet and dementia pathologies, including amyloid and tau markers.