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Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
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Public Health.

Hannah R Speaks1, Meredith S Duncan1, Erin L Abner1,2

  • 1College of Public Health, University of Kentucky, Lexington, KY, USA.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
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Summary
This summary is machine-generated.

This study found no direct link between hearing trajectories and dementia risk over time. However, hearing status changes may reflect underlying factors associated with both hearing loss and cognitive decline.

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Area of Science:

  • Neuroscience
  • Gerontology
  • Epidemiology

Background:

  • Hearing loss is linked to dementia, but the long-term relationship requires further understanding.
  • Characterizing hearing trajectories can guide interventions for brain health and aging.
  • This research investigates hearing patterns and their connection to dementia using longitudinal data.

Purpose of the Study:

  • To identify distinct hearing trajectories in older adults.
  • To examine the association between these hearing trajectories and the incidence of dementia.
  • To explore relationships between hearing trajectories and known dementia risk factors.

Main Methods:

  • Longitudinal analysis of cognitive normal participants from the National Alzheimer's Coordinating Center (NACC) database (2005-2023).
  • Group-based trajectory modeling to define hearing status groups over time.
  • Logistic mixed-effects models to assess the association between hearing trajectories and dementia status.

Main Results:

  • Three hearing trajectory groups were identified: low function (2.2%), high function (79.3%), and variable hearing loss (18.5%).
  • Baseline non-functional hearing correlated with lower education, hypertension, stroke, and older age.
  • No significant association was found between hearing trajectory group and longitudinal dementia outcomes (p=0.43).

Conclusions:

  • Hearing trajectory over time may offer different insights than baseline hearing status alone.
  • Hearing trajectories might act as a proxy for confounding factors impacting both hearing and dementia.
  • Further research is needed to clarify the complex interplay between hearing changes and cognitive aging.