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Published on: August 22, 2012
Public Health.
Danielle D'Amico1, Brian Tan1, Deanise Berba1
1Baycrest Academy for Research and Education, Toronto, ON, Canada.
Dementia risk scores incorporating age and sex show a stronger link to cognitive function than those using only modifiable factors. Further research is needed to understand how these scores predict cognitive changes over time.
Area of Science:
- Neurology
- Gerontology
- Public Health
Background:
- Dementia risk scores aid in communicating risk to adults aiming to maintain cognitive function.
- Limited research compares how different dementia risk scores associate with cognitive function in community-dwelling adults.
Purpose of the Study:
- To examine the association between five dementia risk scores (CogDrisk, LIBRA, modified LIBRA [mLIBRA], CAIDE, Brain Care Score [BCS]) and cognitive function.
- To compare the predictive power of different scoring algorithms on cognitive health.
Main Methods:
- Study included 253 non-demented adults (mean age 69.6 years, 77% female) from a dementia risk reduction center.
- Cognitive function was assessed using the Brain Health Assessment (BHA) total score.
- Generalized linear models analyzed associations between dementia risk scores and BHA scores.
Main Results:
- Lower CogDrisk, mLIBRA, and CAIDE scores were significantly associated with higher BHA (cognitive function) scores.
- LIBRA and BCS scores did not show a significant association with cognitive function in this cohort.
Conclusions:
- Dementia risk scores including non-modifiable factors (age, sex) demonstrated a stronger association with cognitive function.
- Future longitudinal research is recommended to assess how dementia risk scores predict cognitive changes over time.
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