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Related Concept Videos

Primary Healthcare Services01:30

Primary Healthcare Services

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Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
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Health promotion allows a person to control the determinants of health, resulting in an improved health status. It enhances the quality of life and reduces premature deaths. Health promotion and illness prevention programs help people make beneficial choices to reduce the risk of disease and disabilities. There are three health promotion and illness prevention levels: primary, secondary, and tertiary prevention.
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Preventive Healthcare Services01:30

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Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
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Principles of Disease Surveillance01:26

Principles of Disease Surveillance

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Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
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Healthcare Agencies II01:17

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There are various healthcare agencies in the United States—some of which are managed by religious institutions and others by different government branches.
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Methods Of Healthcare Delivery System01:26

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At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
Managed Care System:
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Public Health.

Jacqueline Pontes Monteiro1, Hannatu Amaza2, Isabella Hoang2

  • 1Wisconsin Alzheimer's Disease Research Center, School of Medicine and Public Health, Madison, WI, USA.

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Summary
This summary is machine-generated.

The Alzheimer's Disease Neuroimaging Initiative (ADNI4) successfully used a community-engaged research (CER) model to boost participant engagement and improve study generalizability. This approach enhanced recruitment from diverse backgrounds, exceeding initial goals for broader data representation.

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Area of Science:

  • Neuroscience and Aging Research
  • Clinical Trial Methodology
  • Community-Based Participatory Research

Background:

  • Ensuring the generalizability of Alzheimer's Disease Neuroimaging Initiative (ADNI) data is crucial for advancing research.
  • The ADNI4 Engagement Core utilizes a multi-pronged community-engaged research (CER) model to enhance participant engagement.
  • This study assesses the preliminary efficacy of the CER model through enrollment updates.

Purpose of the Study:

  • To implement and evaluate a community-engaged research (CER) model within ADNI4 to improve participant engagement.
  • To increase the generalizability of ADNI study data by engaging diverse populations.
  • To assess the effectiveness of specific CER strategies, including partnerships with Community-Based Organizations (CBOs) and the deployment of Community Research Liaisons (CRLs) and Community Research Navigators (CRNs).

Main Methods:

  • A CER model prioritizing trust-building, co-learning, and power-sharing with CBOs and participants across all ADNI4 phases.
  • Partnership with "Hub Sites" providing support for participant engagement, including dedicated CRLs.
  • Remote support from CRNs via phone, email, and chat to address participant needs and build relationships.

Main Results:

  • As of January 2025, 10 Hub Sites, 6 CRLs, and 6 CRNs were active, engaging 85 CBOs and reaching 7,994 individuals through 101 community events.
  • CRNs managed 3,124 communications, primarily addressing blood biomarkers, enrollment, and study-related inquiries.
  • The 10 Hub Sites, representing approximately 20% of ADNI sites, contributed to about 50% of the improved generalizability in new in-clinic enrollees.

Conclusions:

  • ADNI4 has successfully scaled a comprehensive CER model nationwide, demonstrating increased participant engagement and generalizability.
  • The implemented strategies, focused on trust and long-term community partnerships, exceeded study goals.
  • This approach offers a replicable and scalable model for generating more generalizable data in the Alzheimer's Disease and Related Dementias (AD/ADRD) field.