Related Experiment Video
Updated: Jan 8, 2026
Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
Published on: August 22, 2012
Public Health
So Yeon Jeon1,2, Min Soo Byun3,4,5, Hyeji Choi3
1Chungnam National University Hospital, Daejeon, Daejeon, Korea, Republic of (South).
This study estimates lecanemab eligibility in Korea, finding only 14.4% of clinic patients and 8.3% of cohort participants met criteria. These findings suggest a need for tailored guidelines for Alzheimer's disease treatment in South Korea.
Area of Science:
- Neurology
- Clinical Research
- Alzheimer's Disease
Background:
- Lecanemab, approved in South Korea in May 2024, has limited real-world eligibility data.
- Estimating lecanemab eligibility is crucial for guiding treatment access in the Korean population.
Purpose of the Study:
- To estimate the proportion of patients eligible for lecanemab treatment in Korea.
- To assess eligibility in both a clinical memory clinic population and a research cohort.
Main Methods:
- Retrospective analysis of 2,726 patients from a university memory clinic and 625 from the KBASE cohort.
- Applied ADRD-TWG Appropriate Use Recommendations (AUR) for lecanemab eligibility criteria.
- Included MMSE score criteria (≥22 or z-score > -1.5) and amyloid PET positivity.
Main Results:
- In the clinical sample, 14.4% were eligible after applying all criteria.
- In the cohort sample, 8.3% were eligible after applying all criteria.
- The overall estimated eligibility across both groups was 8.7%.
Conclusions:
- This study provides the first real-world lecanemab eligibility data for the Korean population.
- Current guidelines may exclude a significant proportion of early Alzheimer's disease patients.
- Tailored eligibility criteria reflecting Korean population characteristics and healthcare access are needed.
More Related Videos
09:33Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India
Published on: December 23, 2022
07:20Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
Published on: January 28, 2014
Related Concept Videos
01:30Primary Healthcare Services
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
01:26Levels of Health Promotion and Illness Prevention
In primary prevention, actions taken before disease onset prevent the disease from...
01:30Preventive Healthcare Services
01:26Principles of Disease Surveillance
01:17Healthcare Agencies II
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources,...
01:26Methods Of Healthcare Delivery System
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...