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Related Concept Videos

Primary Healthcare Services01:30

Primary Healthcare Services

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Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
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Health promotion allows a person to control the determinants of health, resulting in an improved health status. It enhances the quality of life and reduces premature deaths. Health promotion and illness prevention programs help people make beneficial choices to reduce the risk of disease and disabilities. There are three health promotion and illness prevention levels: primary, secondary, and tertiary prevention.
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Preventive Healthcare Services01:30

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Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
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Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
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Healthcare Agencies II01:17

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There are various healthcare agencies in the United States—some of which are managed by religious institutions and others by different government branches.
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At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
Managed Care System:
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Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
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Public Health.

Rhaná Carolina Santos1,2, Julia Reis Mathias3, Sonia Maria Dozzi Brucki4,5,6

  • 1Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 23, 2025
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Summary
This summary is machine-generated.

Donanemab treatment for Alzheimer's Disease (AD) may be cost-effective in Brazil. Delaying dementia progression with anti-amyloid drugs could save costs for the Brazilian healthcare system.

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Area of Science:

  • Health Economics
  • Neurology
  • Pharmacoeconomics

Background:

  • Anti-amyloid drugs show promise for delaying dementia progression.
  • High treatment costs limit access in Low and Middle-Income Countries (LMICs).
  • This study evaluates the cost-effectiveness of Donanemab for Alzheimer's Disease (AD) within Brazil's healthcare system.

Purpose of the Study:

  • To assess the potential cost savings of using Donanemab for Alzheimer's Disease (AD) in Brazil.
  • To determine the economic viability of anti-amyloid therapies in the Brazilian context.
  • To analyze the impact of delaying dementia progression on overall healthcare costs.

Main Methods:

  • Systematic review of dementia cost studies in Brazil (1997-2024).
  • Sourcing Donanemab costs from industry reports.
  • Cost-saving analysis comparing healthcare expenditures for mild and moderate AD, considering a 5.3-month delay in progression.

Main Results:

  • Dementia costs in Brazil range from USD 536.27 to USD 1,376.28.
  • Monthly costs for mild, moderate, and severe dementia are estimated at USD 1,000, USD 1,700, and USD 1,372, respectively.
  • A 5.3-month delay in progression could save approximately USD 3,710; the cost-saving threshold for Donanemab viability is around USD 210 monthly.

Conclusions:

  • Anti-amyloid treatment, like Donanemab, can potentially reduce dementia costs in Brazil.
  • The strategy may become cost-effective, especially considering Brazil's 1.2 million AD patients.
  • Results highlight significant economic implications for public health policies and the healthcare system.