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Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
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Updated: Jan 8, 2026

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
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Public Health.

Yi Zhao1, Liangjun Dang2, Suhang Shang2

  • 1The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, shaanxi, China.

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|December 23, 2025
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Summary
This summary is machine-generated.

Elevated plasma oxidized low-density lipoprotein (ox-LDL) levels are linked to a higher risk of cognitive impairment in Chinese adults over 40. Further research is needed to confirm a causal relationship between ox-LDL and cognitive decline.

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Area of Science:

  • Cardiovascular Research
  • Neuroscience
  • Public Health

Background:

  • Plasma oxidized low-density lipoprotein (ox-LDL) is implicated in atherosclerosis and cardiovascular events.
  • The association between plasma ox-LDL levels and cognitive impairment remains under-investigated.

Purpose of the Study:

  • This study aimed to investigate the relationship between plasma ox-LDL levels and cognitive impairment in a Chinese population aged 40 and above.

Main Methods:

  • A cross-sectional, community-based study included 1,406 participants (≥ 40 years) from Xi'an, China.
  • Cognitive function was assessed using the Mini-Mental State Examination (MMSE) and neuropsychological tests.
  • Plasma ox-LDL levels were measured via ELISA, with statistical analyses including logistic regression and spline analysis.

Main Results:

  • 112 participants (8.0%) were diagnosed with cognitive impairment.
  • A 100-unit increase in plasma ox-LDL was associated with a 9.3% increase in cognitive impairment incidence (OR=1.093).
  • Individuals in the highest ox-LDL tertile had a 1.704-fold higher risk of cognitive impairment compared to the lowest tertile (OR=1.704).

Conclusions:

  • Elevated plasma ox-LDL levels are associated with an increased likelihood of cognitive impairment in Chinese adults aged 40+.
  • The findings highlight a potential link between ox-LDL and cognitive health.
  • Further studies are required to establish a definitive causal relationship.