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Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
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Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
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Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
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Public Health.

Andrea M Russell1, Jeff Williamson2, Wei Huang1

  • 1Northwestern University, Chicago, IL, USA.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 23, 2025
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Summary
This summary is machine-generated.

Blood-based biomarkers (BBMs) for Alzheimer's Disease (AD) are acceptable to primary care patients. Factors like affordability, convenience, and PCP endorsement increase BBM acceptability for adults.

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Area of Science:

  • Biomarkers and Diagnostics
  • Neuroscience and Aging Research
  • Primary Care Medicine

Background:

  • Blood-based biomarkers (BBMs) offer accessible, cost-effective Alzheimer's Disease (AD) detection and monitoring.
  • Patient attitudes and acceptability of BBMs remain understudied in primary care settings.

Purpose of the Study:

  • To assess patient attitudes and acceptability of BBMs for AD in a primary care population.
  • To identify factors influencing patient willingness to use BBMs and their concerns.

Main Methods:

  • A survey was administered to 572 primary care patients aged 30+ in Chicago, IL.
  • Questionnaires assessed attitudes toward BBMs, with analysis using descriptive statistics, chi-squares, and logistic regression.
  • Health literacy (HL) and demographic variables were examined for associations with survey responses.

Main Results:

  • Most participants (96.6%) would complete BBMs if recommended by their PCP, and 87.3% would be motivated to reduce risk after a positive result.
  • Concerns about test accuracy (35.8%) and potential distress (27.5%) varied by education and HL. Women reported higher concern for distress.
  • Acceptability increased with results informing future care (94.6%), insurance coverage (93.9%), convenience (88.3%), pre-test education (88.9%), and PCP endorsement (82.1%).

Conclusions:

  • Blood-based biomarkers (BBMs) demonstrate high acceptability among primary care patients for Alzheimer's Disease (AD) screening.
  • Affordability, clarity on future care implications, and convenience are key drivers for BBM adoption in middle-aged and older adults.
  • Comprehensive pre-test education and PCP support are crucial for addressing patient concerns, including test accuracy and potential distress.