Related Experiment Video
Updated: Jan 8, 2026
Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
Published on: August 22, 2012
Public Health
Selina Quinones1, Joseph M Curran2, Roscoe Bell1
1Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Background:
Blood-based biomarkers (BBMs) provide a less invasive and more accessible alternative to CSF or PET to diagnosis Alzheimer's disease (AD) among individuals with cognitive impairment. However, limited research exists on patient perspectives toward BBMs. BLOOM-AD aims to explore patient attitudes toward BBMs, with a focus on identifying concerns, preferences, and disparities across diverse populations.
Methods:
The BLOOM-AD study will recruit 1500 adults aged 50+ from Atrium Health primary care clinics. Participants will complete a 15-minute survey assessing demographics, clinical health status, personal and family history of memory loss, as well as knowledge and attitudes toward AD and AD-BBMs. Statistical testing will be done across the demographic factors of race/ethnicity, socio-demographics, health status and sex.
Results:
We will have enrolled 1000 patients into the study by April 2025, and the full complement by summer 2025 when data collection will be completed. It is anticipated that this survey will precipitate a high interest in BBMs, particularly if biomarker results inform care planning, testing is covered by insurance, and PCPs endorse its use. However, we expect differences across racial and ethnic lines, with historically marginalized communities showing greater skepticism towards BBMs due to past healthcare inequities. Barriers related to health literacy and mistrust of healthcare services are expected. These findings may identify differences in BBM acceptance and barriers among diverse populations, who historically face greater health disparities in AD diagnosis and care. The results will guide future approaches for equitable, patient-centered implementation of BBMs in primary care.
Conclusions:
The BLOOM-AD study will deepen our understanding of patient perspectives on BBMs in primary care, with a focus on diverse populations. These insights will inform strategies to improve outreach, address disparities, and promote early AD detection and prevention, ensuring equitable access and addressing patient concerns in clinical practice.
More Related Videos
09:33Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India
Published on: December 23, 2022
07:20Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
Published on: January 28, 2014
Related Concept Videos
01:30Primary Healthcare Services
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
01:26Levels of Health Promotion and Illness Prevention
In primary prevention, actions taken before disease onset prevent the disease from...
01:30Preventive Healthcare Services
01:26Principles of Disease Surveillance
01:17Healthcare Agencies II
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources,...
01:26Methods Of Healthcare Delivery System
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...