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Related Experiment Video

Updated: Jan 8, 2026

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
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Public Health.

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  • 1Queen's University Belfast, Belfast, Northern Ireland, United Kingdom.

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Summary

The Harmonised Cognitive Assessment Protocol (HCAP) is validated in a Western clinical setting. This study assesses its accuracy in categorizing cognitive function in older adults, aiding dementia diagnosis.

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Area of Science:

  • Neuroscience
  • Gerontology
  • Clinical Psychology

Background:

  • The Harmonised Cognitive Assessment Protocol (HCAP) is a global standard for assessing cognitive function in aging studies.
  • It categorizes individuals into cognitively normal, impaired but not demented, or likely dementia.
  • This is the first validation of HCAP in a Western clinical population, specifically in Northern Ireland.

Purpose of the Study:

  • To clinically validate the Harmonised Cognitive Assessment Protocol (HCAP) in a Western cohort.
  • To assess the accuracy of HCAP in categorizing cognitive status among participants with and without cognitive impairment.
  • To establish the correlation between HCAP-assigned categories and physician-diagnosed cognitive status.

Main Methods:

  • Recruitment of 80 participants (aged 65+) from memory clinics with diagnoses of mild cognitive impairment (MCI) or dementia, and 40 controls.
  • Administration of the HCAP interview, including a family/friend interview to assess functional status.
  • Assignment of participants to cognitive categories using an established HCAP algorithm and correlation analysis with clinical diagnoses.

Main Results:

  • Recruitment is 91% complete, with an anticipated finish in March 2025.
  • Participants' mean age is 76.8 years, with a mean Mini-Mental State Examination (MMSE) score of 21.9.
  • All participants have completed the HCAP interview, enabling planned statistical analysis.

Conclusions:

  • The HCAP interview effectively combines cognitive assessments and functional status evaluation.
  • This validation study in Northern Ireland is the first of its kind in a Western clinical setting.
  • HCAP shows promise for accurate cognitive status categorization in clinical practice.