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Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
Published on: August 22, 2012
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Public Health
Xiuxiu Huang1, Chengfengyi Yang2, Shifang Zhang2
1School of Nursing, Shanghai Jiao Tong University, Shanghai, Shanghai, China.
Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 23, 2025
Summary
Optimizing daily movement behaviors, like increasing moderate-to-high physical activity, is linked to better cognitive function in older adults at risk for dementia. Replacing sedentary time or sleep with physical activity shows cognitive benefits.
Area of Science:
- Gerontology
- Neuroscience
- Public Health
Background:
- Cognitive decline is a growing concern in aging populations, particularly among those at risk for dementia.
- Understanding modifiable lifestyle factors, such as daily movement patterns, is crucial for maintaining cognitive health.
- 24-hour movement behaviors (24HMB) encompass sleep, sedentary time, and physical activity, all potentially influencing cognition.
Purpose of the Study:
- To investigate the association between the time reallocation of 24-hour movement behaviors (24HMB) and cognitive function.
- To examine how changes in the composition of sleep, sedentary time, and physical activity impact cognition in older adults at risk for dementia.
Main Methods:
- A cross-sectional study design was employed, recruiting community-dwelling older adults at risk for dementia.
- Global cognition was assessed using the Montreal Cognitive Assessment scale.
- 24HMB was objectively measured using wrist-worn ActiGraph devices over seven consecutive days, analyzed with compositional regression and isotemporal substitution models.
Main Results:
- Compositional regression analysis indicated a positive association between time spent in moderate-to-high physical activities and global cognition, even after adjusting for covariates.
- Isotemporal substitution modeling demonstrated that substituting 10-30 minutes of sedentary time or sleep with moderate-to-high physical activities was linked to improved cognitive performance.
- No other significant associations between 24HMB time-use composition and cognitive function were identified.
Conclusions:
- The composition of 24-hour movement behaviors, specifically the allocation of time to moderate-to-high physical activities, is significantly associated with cognitive function in older adults at risk for dementia.
- Shifting time from sedentary behaviors and sleep towards moderate-to-high physical activities may offer a beneficial strategy for enhancing cognitive function in this population.
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