Related Experiment Video
Updated: Jan 8, 2026
Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
Published on: August 22, 2012
Public Health
Wendy Wy Huang1, Shirley Fan2, Wei-Ya Li3
1School of Medicine, University of Limerick, Limerick, Munster, Ireland.
Background:
The growing number of older persons undergoing surgery are at a higher risk of neurocognitive disorder due to multimorbidity and age-related changes. The prevalence of postoperative neurocognitive disorder in this population requires further investigation. This systematic review and meta-analysis aims to estimate the pooled prevalence of perioperative neurocognitive disorder in older non-cardiac surgical patients.
Method:
A comprehensive search of multiple databases was conducted from inception to January 24, 2024. This review included studies of non-cardiac surgical inpatients aged ≥60 years old who underwent perioperative cognitive assessments. The primary outcome was the prevalence of postoperative neurocognitive disorder or cognitive dysfunction (POCD). Data were analyzed using a random-effects model to calculate pooled prevalence rates. Quality assessment employed the Newcastle-Ottawa Scale and MOOSE guidelines. Meta-regression was performed with Open Meta Analyst and RStudio 4.3.3.
Result:
Thirty-nine studies (n = 12,921) were included with mean age of 70.0 ± 8.9 years and 44.3% women. The overall prevalence of POCD was 23% (95% CI: 20%, 27%) at day 7, 16% (95% CI: 7%, 25%) at 1 month, 10% (95% CI: 8%, 13%) at 3 months and 3% (95% CI: 2%, 4%) at 1 year (Figure 1). Our meta-regression showed a higher prevalence of POCD in abdominal surgery at day 7 (β = 0.13, 95% CI: 0.03-0.22, p = 0.01) and 3 months (β = 0.49, 95% CI: 0.40-0.58, p < 0.001), versus orthopedic surgeries.
Conclusion:
The overall prevalence of POCD in older non-cardiac surgical populations was 23%, 16%, 10%, and 3% at day 7, 1 month, 3 months, and 1 year, respectively. Abdominal surgery had a higher prevalence of POCD than orthopedic surgery. The significant risk of POCD calls for cognitive screening, risk mitigation and intervention to provide better perioperative care and improve surgical outcomes.
More Related Videos
09:33Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India
Published on: December 23, 2022
07:20Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
Published on: January 28, 2014
Related Concept Videos
01:30Primary Healthcare Services
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
01:26Levels of Health Promotion and Illness Prevention
In primary prevention, actions taken before disease onset prevent the disease from...
01:30Preventive Healthcare Services
01:26Principles of Disease Surveillance
01:17Healthcare Agencies II
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources,...
01:26Methods Of Healthcare Delivery System
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...