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A single-tube RAA-CRISPR-Cas12a diagnostic platform for rapid detection of Chlamydia trachomatis

Tong Jiang1, Pei He2, Yong Guo3

  • 1Department of Clinical Laboratory, Suzhou TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Suzhou, Jiangsu, 215000, China. jt18269857923@163.com.

Journal of Biological Engineering
|December 23, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Chlamydia trachomatisCRISPR-Cas12Clinical diagnosisRecombinase-aided isothermal amplificationSexually transmitted infection

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Bacterial Phylum Chlamydiae01:29

Bacterial Phylum Chlamydiae

The phylum Chlamydiae or Chlamydiota is composed of a single order, Chlamydiales. This phylum consists entirely of obligate intracellular parasites that infect eukaryotic hosts. While human pathogens within this group have been studied extensively, the phylum encompasses many species capable of interacting with various eukaryotic organisms. Members of Chlamydiae are typically small cocci, approximately 0.5 μm in diameter, and exhibit a distinctive developmental cycle. As is characteristic...
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