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Related Concept Videos

Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
Phase Contrast and Differential Interference Contrast Microscopy01:26

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Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
Overview of Electron Microscopy01:25

Overview of Electron Microscopy

The wavelengths of visible light ultimately limit the maximum theoretical resolution of images created by light microscopes. Most light microscopes can only magnify 1000X, and a few can magnify up to 1500X. Electrons, like electromagnetic radiation, can behave like waves, but with wavelengths of 0.005 nm, they produce significantly greater resolution up to 0.05 nm as compared to 500 nm for visible light. An electron microscope (EM) can create a sharp image that is magnified up to 2,000,000X.
Overview of Microscopy Techniques01:22

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The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...

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Measurement of Quantum Interference in a Silicon Ring Resonator Photon Source
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Single-Particle Photothermal Microscopy Using On-Chip Silicon Nitride Microring Resonators.

Yulia Podorova1, Cecilia H Vollbrecht1, Samantha J Evans1

  • 1Department of Chemistry, University of Wisconsin-Madison, 1101 University Ave, Madison, Wisconsin 53706, United States.

The Journal of Physical Chemistry. A
|December 24, 2025
PubMed
Summary
This summary is machine-generated.

Silicon nitride microring resonators (MRRs) enable sensitive single-particle photothermal microscopy. This study calibrated the technique using carbon nanotubes, validating its potential for nanoscale thermal detection.

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Area of Science:

  • Photonics
  • Nanotechnology
  • Microscopy

Background:

  • Optical microresonators offer high sensitivity for detecting thermal changes.
  • On-chip integrated devices are crucial for advanced sensing applications.

Purpose of the Study:

  • Investigate silicon nitride microring resonators (MRRs) for single-particle photothermal microscopy.
  • Calibrate the technique and assess the MRR geometry for microscopy.

Main Methods:

  • Utilized on-chip integrated silicon nitride microring resonators (MRRs).
  • Employed single nonphotoluminescent carbon nanotubes for calibration.
  • Performed finite-element simulations to analyze thermal gradients.

Main Results:

  • Determined absorption cross-section per atom for carbon nanotubes, matching literature values.
  • Successfully demonstrated single-particle photothermal microscopy using MRRs.
  • Quantified thermal gradients relevant to the planar MRR geometry.

Conclusions:

  • The study validates MRRs as a viable platform for sensitive single-particle photothermal microscopy.
  • Finite-element simulations provide crucial insights into thermal dynamics.
  • The planar MRR geometry presents specific advantages and limitations for this application.