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Global Trends in MPOX Research (2014-2025): A Bibliometric Analysis and Overview
Lulu Xie1, Yimin Zhou1, Xinyu Zhang1
1Wenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, 325035, People's Republic of China.
The 2022 monkeypox outbreak spurred significant global research, particularly on viral transmission and clinical interventions. International collaboration intensified, highlighting the need for continued cooperation against future epidemics.
Area of Science:
- Epidemiology
- Virology
- Bibliometrics
Background:
- The 2022 global monkeypox outbreak led to a substantial increase in scientific research.
- Existing studies often lack the latest data and comprehensive analysis of research trends and collaborations.
Purpose of the Study:
- To conduct a bibliometric analysis of monkeypox research from 2014 to 2025.
- To identify research trends, collaboration patterns, and the impact of the Public Health Emergency of International Concern (PHEIC).
Main Methods:
- Bibliometric analysis of 2,076 articles from the Web of Science Core Collection (January 2014 - June 2025).
- Visualization of keyword co-occurrence, country, and institutional collaboration networks using VOSviewer.
- Inclusion of the latest data (2024-2025) and analysis of post-outbreak trends.
Main Results:
- Global research output showed three stages: low accumulation (2014-2021), a sharp surge post-2022, and a peak in 2023.
- Key research areas included viral transmission dynamics and clinical interventions.
- The US led country contributions, followed by China, India, and Saudi Arabia, with significant collaboration between health agencies and academic institutions.
Conclusions:
- The PHEIC effectively concentrated scientific resources for monkeypox research.
- Strengthening international collaboration is crucial for effectively managing future epidemic challenges.
- The study provides a dynamic and multifaceted analysis of the evolving research landscape.
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