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Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
"Hadrontherapy for Life" Symposium, Caen, March 10/11, 2025-Strategy for the Future-Pediatric Tumors
Jean-Louis Habrand1, Semi B Harrabi2, Shigeru Yamada3
1Radiation Oncology Department, François Baclesse Cancer Center, Caen, France.
None:
The symposium "Hadrontherapy for life," held in Caen, on March 10 and 11, 2025, brought together over 100 international experts of heavy ions particle therapy. Clinical aspects of current indications and future strategies were discussed. If protontherapy remains the cornerstone of current strategies dealing with pediatric malignancies, in order to better spare normal tissues from deleterious effects of radiation, heavier ions such as carbon ions could play a role in selected highly radio-resistant processes such as bone and non rhabdomyosrcomas soft tissue sarcomas. A special mention should be made to helium ions tested since 2021 in Europe that mimic protons with further ballistic selectivity. If immediate and early side effects of heavy ions look modest, long-term tolerance still needs to be carefully evaluated, including risks of carcinogenesis.
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