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Updated: Jan 8, 2026

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Charters in Patient-Engaged Research: A Scoping Review of Current Evidence.

Jenny Martínez1, Catherine Verrier Piersol2, Richard W Hass1

  • 1College of Population Health Thomas Jefferson University Philadelphia Pennsylvania USA.

Public Health Challenges
|December 24, 2025
PubMed
Summary
This summary is machine-generated.

Collaboratively developed research study charters improve shared governance and power sharing in patient-engaged research. Ensuring charters are valid, systematic, and inclusive enhances research partnerships and quality.

Keywords:
comparative effectiveness researchmethodologypatient engagementsystematic reviewtranslational research

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Area of Science:

  • Health Services Research
  • Patient and Community Engagement in Research
  • Collaborative Governance Models

Background:

  • Research study charters are crucial for establishing shared governance and power dynamics in collaborative research.
  • These charters are negotiated individually for each study, reflecting unique partnership dynamics and priorities.
  • Understanding the development, structure, and implementation of these charters is vital for effective patient-engaged research.

Purpose of the Study:

  • To systematically review and synthesize existing evidence on the creation, components, and application of research study charters.
  • To map the landscape of study charters utilized within patient-engaged research initiatives.
  • To identify best practices and variations in the use of research study charters.

Main Methods:

  • A comprehensive search of peer-reviewed literature published globally in English from January 2019 to January 2025.
  • Inclusion of 17 citations, comprising 5 journal articles and 12 study charters sourced from the Patient-Centered Outcomes Research Institute (PCORI) repository.
  • Analysis focused on the development, structure, and implementation aspects of the identified study charters.

Main Results:

  • The review identified a range of research study charters with significant variability in their quality, level of detail, and methodological approaches.
  • Development processes, structural elements, and content of study charters were not uniform across the reviewed literature.
  • A notable portion of reviewed charters were sourced from PCORI's Engagement Tool and Resource Repository.

Conclusions:

  • Research study charters exhibit considerable variation in quality, detail, and methodology.
  • The development of valid, systematic, and inclusive study charters, co-created with research partners, is essential for enhancing governance and engagement.
  • Adopting well-developed charters can significantly improve the quality and inclusivity of patient-centered research, warranting further investigation.