Charters in Patient-Engaged Research: A Scoping Review of Current Evidence

Research study charters facilitate shared governance and power sharing with research partners when developed collaboratively and early on in a study. Study charters are negotiated and developed on a study-by-study basis, offering insight into study-specific dynamics between research partners and investigators, as well as the factors that each identify as important for their collaboration. This review aimed to map and synthesize existing evidence on the development, structure, and implementation of research study charters used in patient-engaged research.

We searched peer-reviewed literature published worldwide in English between January 2019 and January 2025.

Our final sample consisted of 17 citations, including 5 journal articles and 12 charters available on Patient-Centered Outcomes Research Institute's (PCORI's) Engagement Tool and Resource Repository. Research study charters varied in their development, structure, and content.

We identified research study charters that varied in quality, detail, and methods. Valid, systematic, and inclusive study charters that are developed with research partners and reflect a diversity of perspectives can improve governance and engagement in research partnerships. Their adoption may enhance the quality and inclusivity of patient-centered research and represent an important area for future investigation.