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Fertilization

Fertilization

During fertilization, an egg and sperm cell fuse to create a new diploid structure. In humans, the process occurs once the egg has been released from the ovary, and travels into the fallopian tubes. The process requires several key steps: 1) sperm present in the genital tract must locate the egg; 2) once there, sperm need to release enzymes to help them burrow through the protective zona pellucida of the egg; and 3) the membranes of a single sperm cell and egg must fuse, with the sperm...

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Updated: Jan 8, 2026

Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues

Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues

Published on: October 20, 2019

Complete hydatidiform mole with coexisting fetus: A case report.

Yuanhua Xiang¹, Wei Zhang¹, Dongmin Chen¹

¹Department of Ultrasound Medicine, Taizhou Hospital of Zhejiang Province Affiliated With Wenzhou Medical University, Taizhou 317000, Zhejiang, China.

Case Reports in Women'S Health

|December 24, 2025

Summary

Complete hydatidiform mole with coexisting fetus (CHMCF) is rare, posing diagnostic and management challenges. Early suspicion, genetic analysis, and careful surveillance are crucial for optimal outcomes.

Area of Science:

Obstetrics and Gynecology
Reproductive Endocrinology
Medical Genetics

Background:

Complete hydatidiform mole with coexisting fetus (CHMCF) is an exceptionally rare obstetric complication.

Keywords:

Coexisting fetus Complete hydatidiform mole Gestational trophoblastic neoplasia Prenatal diagnosis β-human chorionic gonadotropin

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Diagnosis and management necessitate a high index of suspicion and a multidisciplinary approach.