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Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

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Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
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Related Experiment Video

Updated: Jan 8, 2026

Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns
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Digital screening mammograms: current status and future prospects.

Benjamin Hyams1, Kathryn P Lowry2,3, Karla Kerlikowske4,5

  • 1School of Medicine, University of California, San Francisco, CA, USA.

Expert Review of Medical Devices
|December 24, 2025
PubMed
Summary
This summary is machine-generated.

Emerging mammography technologies show promise in improving cancer detection rates. However, their impact on reducing interval and advanced cancers requires further research and real-world evaluation for patient benefit.

Keywords:
Breast cancerartificial intelligencecontrast enhanced mammographydigital breast tomosynthesismammographyscreening

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Area of Science:

  • Radiology and Medical Imaging
  • Oncology
  • Biomedical Engineering

Background:

  • Mammography is a vital breast cancer screening tool, but faces limitations like reduced sensitivity in dense breasts and overdiagnosis.
  • Emerging technologies aim to overcome these challenges and enhance screening efficacy.

Purpose of the Study:

  • To review emerging mammography technologies and their assessment endpoints.
  • To evaluate the clinical impact of digital breast tomosynthesis (DBT), contrast-enhanced mammography (CEM), and artificial intelligence (AI) in mammography.

Main Methods:

  • Review of clinical trial data for DBT, focusing on interval and advanced cancer rates.
  • Assessment of CEM as a supplemental screening tool for dense breasts.
  • Overview of AI applications in mammography for lesion detection, triage, density assessment, and risk prediction.

Main Results:

  • Emerging technologies show improved surrogate endpoints like cancer detection.
  • Evidence for reducing clinically meaningful outcomes (interval/advanced cancers) is still developing.
  • DBT performance varies between average-risk and high-risk populations.

Conclusions:

  • While new mammography technologies improve cancer detection, their effect on reducing interval and advanced cancers needs more robust evidence.
  • Future research must prioritize clinically relevant endpoints and real-world validation to ensure patient benefit.