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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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Synthesis of 5-Hydroxy-5-vinyl-2-cyclopentenones, a Family of Rare-Type Natural Products Mostly Recovered from Marine

Yoshihide Usami1, Natsuki Asada1, Chihiro Shizuma1

  • 1Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Osaka Medical and Pharmaceutical University, 4-20-1 Nasahara, Takatsuki 569-1094, Japan.

Marine Drugs
|December 24, 2025
PubMed

Keywords:
5-hydroxy-5-vinyl-2-cyclopentenoneMislow-Evans rearrangementconjugate additionmicrowave-aided reactionnatural productracemicsynthesis

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