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The CanCURE Survey: Gender-Based Differences in HIV Cure Research Priorities.

Jessica Lu1, Branka Vulesevic2, Shari Margolese3

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Journal of Personalized Medicine
|December 24, 2025
PubMed
Summary
This summary is machine-generated.

Men and women with HIV share some cure research priorities, but differ on others. Gender disparities in interventional study participation highlight the need to align research with diverse concerns.

Keywords:
HIVHIV cure researchcommunity engagementgender differencesresearch prioritieswomen with HIV

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Area of Science:

  • Public Health
  • HIV Research
  • Gender Studies

Background:

  • The Canadian HIV Cure Enterprise (CanCURE) is a research collaboratory focused on sustainable HIV remission.
  • A co-designed web-based survey identified HIV research priorities among people with HIV (PWH) in Canada.
  • This study specifically examined gender-based differences in these priorities.

Purpose of the Study:

  • To identify and analyze gender-specific research priorities for HIV cure among PWH in Canada.
  • To understand how gender influences the perspectives on HIV cure research.

Main Methods:

  • A cross-Canada web-based survey was conducted from August to December 2024.
  • 109 people with HIV (PWH) completed surveys on demographics, HIV knowledge, and research priorities.
  • Priorities were ranked on a scale, and data were stratified by gender.

Main Results:

  • Significant gender differences emerged in HIV cure research priorities.
  • Men prioritized preventing HIV transmission and studying viral reservoirs; women prioritized daily pill avoidance and comorbidity risks.
  • Men were three times more likely than women to have participated in interventional studies.

Conclusions:

  • While some HIV cure research priorities are shared, notable gender-specific concerns exist.
  • A significant gender gap in interventional study participation requires attention.
  • Aligning research priorities with the concerns of both genders is crucial for advancing HIV cure research.