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Mitochondrial-Immune Overlap in Leber Hereditary Optic Neuropathy: A Case Report and Lessons Learned

Hind Alnajashi1,2, Walid Eltantawi3

  • 1Department of Neurology, Faculty of Medicine, King Abdulaziz University, Jeddah P.O. Box 80200, Saudi Arabia.

Reports (MDPI)
|December 24, 2025
PubMed
Summary

Leber hereditary optic neuropathy (LHON) can mimic multiple sclerosis (MS) symptoms. Recognizing red flags like poor vision recovery is crucial for diagnosing this mitochondrial-immune overlap disorder and guiding treatment.

Keywords:
Harding’s diseaseLeber hereditary optic neuropathy (LHON)mitochondrial dysfunctionmultiple sclerosis (MS)optic neuritistransverse myelitis

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