Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

749
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
749
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

516
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
516

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tunable opto-magnetic metamaterials <i>via</i> coupled TiN-NiO vertically aligned nanocomposite thin films.

Nanoscale·2026
Same author

Rb<sub>2</sub>ZnGe<sub>3</sub>Se<sub>8</sub>: A Large-Birefringence Layered Chalcogenide Enabled by Anisotropic Electrons in Tetrahedral Units.

Inorganic chemistry·2026
Same author

Molybdenum nanoparticle improved seed germination in Kale via regulating ROS homeostasis and metabolites accumulation under salinity stress.

Frontiers in plant science·2026
Same author

<i>In Situ</i> Study of the Ferroelectric-Antiferroelectric Phase Transition in Hf<sub>1-<i>x</i></sub>Zr<sub><i>x</i></sub>O<sub>2</sub> at Elevated Temperatures up to 600 °C.

Nano letters·2026
Same author

The Cardiovascular Safety of Antiparkinsonian Drugs-Analysis of Signals in the FDA Adverse Event Report System Database.

Basic & clinical pharmacology & toxicology·2026
Same author

Broadband infrared-transparent crystals enabled by heterologous isomorphic substitution.

Dalton transactions (Cambridge, England : 2003)·2026
Same journal

Unveiling the procoagulant state in Alzheimer's disease: A novel PET imaging strategy.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Estimated labor market outcomes of people progressing from preclinical to early-stage Alzheimer's disease in the United States.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Amyloid exacerbates tau and alpha-synuclein pathologies, behavioral impairments, and neuroinflammation in a mixed dementia model.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Multimorbidity burden and patterns associated with DeepBrainNet-derived brain-age gap in dementia-free older adults: A community-based study.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Reply to "Shifting the emphasis of brain health literacy from individuals to systems to reduce inequalities".

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Shifting the emphasis of brain health literacy from individuals to systems to reduce inequalities.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
See all related articles

Related Experiment Video

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

Biomarkers.

Wenzhi Shi1, Peiyao Wei1, Juanjuan Lu1

  • 1Shaanxi Provincial People's Hospital, Xi'an, Shaanxi Provincial, China.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 24, 2025
PubMed
Summary
This summary is machine-generated.

The LDL-C/ApoB ratio, a marker of LDL particle size, is a significant risk factor for cardiovascular incidents (CI) in older adults. Maintaining an optimal ratio may be crucial for preventing CI.

More Related Videos

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

Related Experiment Videos

Last Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

Area of Science:

  • Cardiovascular Medicine
  • Lipid Metabolism
  • Geriatric Health

Background:

  • Elevated Apolipoprotein B (ApoB) and LDL-C levels are linked to cardiovascular incidents (CI).
  • The LDL-C/ApoB ratio indicates LDL particle size; smaller, denser LDL (sdLDL) particles are more atherogenic.
  • The precise relationship between the LDL-C/ApoB ratio and CI requires further elucidation.

Purpose of the Study:

  • To investigate the association between the LDL-C/ApoB ratio and cardiovascular incidents (CI) in individuals over 60.
  • To explore potential nonlinear relationships between the LDL-C/ApoB ratio and CI.

Main Methods:

  • Utilized data from the National Health and Nutrition Examination Survey (NHANES) from 2011-2014.
  • Included 1,105 participants aged over 60.
  • Employed logistic regression and restricted cubic splines (RCS) analyses.

Main Results:

  • Logistic regression revealed a significant association between the LDL-C/ApoB ratio and CI (OR: 1.519, p < 0.001), but not ApoB alone (OR: 1.003, p = 0.215).
  • These findings persisted after adjusting for age and gender (OR: 1.349, p < 0.05).
  • RCS analysis demonstrated a significant nonlinear relationship between the LDL-C/ApoB ratio and CI (Pnon-linear < 0.0001), even after adjustments.

Conclusions:

  • The LDL-C/ApoB ratio is identified as a potential risk factor for CI in the elderly population.
  • An optimal LDL-C/ApoB ratio may play a vital role in the prevention of cardiovascular incidents.