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Related Concept Videos

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

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Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
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Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
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Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

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Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
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Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
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Biomarkers.

Ethan Draper1, Jasmine Cakmak2, Kesavi Kanagasabai3

  • 1Montreal Neurological Institute, Montreal, QC, Canada.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 24, 2025
PubMed
Summary
This summary is machine-generated.

CONNExIN trained 34 African students and clinicians in neuroimaging analysis for dementia research, enhancing local expertise in low- and middle-income countries (LMICs). This initiative aims to build sustainable capacity for advanced brain imaging research.

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Area of Science:

  • Neuroimaging
  • Dementia Research
  • Medical Education

Background:

  • Positron emission tomography (PET) and magnetic resonance imaging (MRI) are crucial for dementia diagnosis and biomarker research.
  • Access to advanced neuroimaging techniques is increasing in low- and middle-income countries (LMICs).
  • A significant gap exists in trained research personnel within LMICs for neuroimaging data analysis.

Purpose of the Study:

  • To address the shortage of trained personnel in LMICs for neuroimaging analysis in dementia research.
  • To implement a hybrid training initiative (CONNExIN) utilizing the Teach-Try-Use strategy.
  • To foster local expertise capable of conducting and disseminating dementia imaging research.

Main Methods:

  • CONNExIN, a hybrid initiative, employed seminars and hands-on training for MRI and PET analysis.
  • Multi-scanner brain MRI data from healthy volunteers were used for training purposes across six sites.
  • A 16-week program included virtual self-paced learning, weekend tutorials, and a hybrid bootcamp with on-site and virtual participation.

Main Results:

  • 34 students and clinicians from 6 countries completed the 16-week training program.
  • Participants analyzed both local and open-access brain scans across various MRI and PET modalities.
  • A total of 120 hours of no-cost training in neuroimaging analysis and dementia research was delivered.

Conclusions:

  • CONNExIN successfully trained a cohort in neuroimaging data analysis, establishing local experts in LMICs.
  • The program enhances dementia imaging research capacity by empowering local professionals to train others.
  • Training materials will be disseminated via protocols.io to promote wider adoption and knowledge sharing.