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Related Concept Videos

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

749
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
749
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

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Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
516

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Related Experiment Video

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

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Biomarkers.

Jiajia Fu1, Xueping Chen1, Huifang Shang1

  • 1West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 24, 2025
PubMed
Summary
This summary is machine-generated.

Nutritional and metabolic factors significantly impact Alzheimer's disease (AD) risk. Poor nutrition and metabolic issues, like liver and pancreas disturbances, may serve as early AD biomarkers, highlighting the need for monitoring these prodromal indicators.

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Area of Science:

  • Neurology
  • Metabolic Medicine
  • Nutritional Science

Background:

  • Alzheimer's disease (AD) is influenced by nutritional and metabolic factors.
  • Large-scale prospective studies on pre-onset AD changes are lacking.
  • This study investigates temporal changes in body composition and metabolic biomarkers before AD onset.

Purpose of the Study:

  • To comprehensively analyze temporal changes in body composition and blood nutritional metabolic biomarkers preceding AD.
  • To assess the influence of these factors on AD risk using the UK Biobank database.

Main Methods:

  • Utilized the UK Biobank database (2006-2010) with 226,328 participants.
  • Included individuals with body composition assessments and blood tests; 1,283 developed AD.
  • Employed Cox regression analysis and nested case-control studies.

Main Results:

  • Elevated fat mass and fat-free mass decreased AD risk.
  • Cholesterol (TC) and LDL-C showed non-linear associations with AD risk.
  • Increased sex hormone-binding globulin (SHBG) and aspartate aminotransferase levels, along with diabetes, elevated AD risk.
  • Pre-AD onset, patients had lower weight, vitamin D, and body composition, but higher SHBG and aspartate aminotransferase.

Conclusions:

  • Poor nutritional status and metabolic disturbances (liver, pancreas) increase AD incidence.
  • These factors may act as early biomarkers in the preclinical stage of AD.
  • Monitoring prodromal biomarkers is crucial for early AD detection and management.