Biomarkers

Area of Science:

• Neuroscience
• Digital Health
• Gerontology

Background:

• Remote digital cognitive assessments hold significant potential for addressing unmet needs in global healthcare, particularly for early Alzheimer's disease (AD) detection and progression monitoring.
• Current limitations in legacy approaches necessitate new frameworks for effective deployment of these technologies.
• Establishing best practices is crucial for maximizing benefits for both users and healthcare providers.

Purpose of the Study:

• To establish a framework and standards for the future use of remote digital cognitive assessments in early Alzheimer's disease (AD).
• To address the need for standardized systems and best practices in deploying remote digital tools for AD management.

Main Methods:

• Convening a multinational and multidisciplinary expert group (REMOTE-AD) funded by the EU Joint Programme on Neurodegenerative Disease Research (JPND).
• Structuring work into four groups focusing on unmet needs, framework development, social/ethical considerations, and implementation systems.
• Conducting workshops to define scope and finalize recommendations for remote digital assessment frameworks.

Main Results:

• Identifying unmet needs in AD clinical practice suitable for remote digital assessment.
• Developing a framework for appraising appropriate measures and technologies for various use cases.
• Evaluating social and ethical considerations for deploying remote digital assessments.
• Designing systems for the future implementation of these tools.

Conclusions:

• Remote digital tools are integral to the future of AD management.
• Current deployment plans are hindered by the lack of established frameworks and systems.
• The REMOTE-AD initiative aims to provide these essential frameworks, benefiting healthcare services globally.