Discharge Strategies Following Successful Ileocolic Intussusception Reduction: Hospitalization vs Emergency

Daniel M Cohen1, Sara Helwig1, Naveen Poonai2

  • 1Department of Pediatrics, The Ohio State University and Nationwide Children's, Columbus, OH.

The Journal of Pediatrics
|December 24, 2025
PubMed

Insights

Discharging children from the emergency department after ileocolic intussusception reduction may increase return visits. However, both emergency department discharge and inpatient hospitalization show high success rates for recurrent intussusception re-reduction.

Area of Science:

  • Pediatric Gastroenterology
  • Emergency Medicine
  • Surgical Outcomes

Background:

  • Ileocolic intussusception (ICI) is a common pediatric surgical emergency.
  • Successful reduction of intussusception can be followed by different discharge strategies.
  • Comparing inpatient hospitalization versus emergency department (ED) observation/discharge is crucial for optimizing care.

Purpose of the Study:

  • To compare the effectiveness and safety of two discharge strategies after successful ileocolic intussusception reduction.
  • To evaluate the rates of recurrent intussusception (re-ICI) and return to the ED based on discharge disposition.
  • To inform clinical decision-making regarding hospitalization versus ED discharge for children with ICI.

Main Methods:

  • A planned secondary analysis of a large international cohort of children (4 months to 4 years) with successful ICI reduction.
  • Data collected from 86 pediatric centers across 14 countries (2017-2019).
  • Evaluation of associations between discharge strategy (inpatient vs. ED discharge) and outcomes like ED return for re-ICI within 48 hours and the study period.

Main Results:

  • 2,686 ICI cases analyzed; 59% hospitalized, 41% discharged from ED.
  • Overall ED return for ICI was 8.9%; 10.2% of ED-discharged patients returned vs. 7.9% of hospitalized patients.
  • Patients discharged from the ED had a significantly higher odds of return within 48 hours (aOR=3.43) and within the study period (aOR=1.48) compared to hospitalized patients.
  • Re-reduction success rates were high and comparable in both groups (83.9%–94.1%).

Conclusions:

  • While ED discharge after successful ICI reduction may be associated with a higher risk of return visits for recurrent intussusception, the rates of successful re-reduction remain high.
  • The findings suggest that individualized assessment of risks and benefits is essential.
  • Clinicians should consider patient-specific factors to potentially avoid unnecessary hospitalizations while ensuring safety.
Abstract

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