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Clinical Manifestations.

Jennifer Woodward1, Timothy Ryan Smith2, Jill K Morris3

  • 1University of Kansas Medical Center, Department of Family Medicine, Kansas City, KS, USA.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 24, 2025
PubMed
Summary
This summary is machine-generated.

Primary care providers can now systematically detect dementia earlier using new tools and collaborative care. This model empowers them to improve diagnosis and access to timely, high-quality dementia care.

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Area of Science:

  • Neurology
  • Primary Care Medicine
  • Healthcare Systems

Background:

  • The advent of blood-based biomarkers (e.g., ptau217) and anti-amyloid therapies necessitates earlier dementia detection in primary care.
  • Primary care providers (PCPs) often face challenges incorporating these advancements due to limited tools, training, and time.
  • The University of Kansas Health System (UKHS) developed a system-wide model to address these challenges and improve dementia care.

Purpose of the Study:

  • To implement and evaluate a health-system-wide model aimed at empowering PCPs for earlier and more systematic dementia detection.
  • To integrate innovations like blood biomarkers and collaborative care into routine primary care practice.
  • To enhance diagnostic confidence and streamline dementia care pathways.

Main Methods:

  • The Brain Health Care Accelerator program integrates standardized workflows, clinical decision support, blood biomarker testing (ptau217), and collaborative care.
  • Key components include a "Cognitive Assessment Visit" template and specialized referral pathways to memory care sub-clinics.
  • Collaborative care models ensure PCPs remain central, with options for e-consultation, complex diagnostics, anti-amyloid treatment, and long-term memory support.

Main Results:

  • Systematic data collection on time-to-diagnosis, referral, treatment initiation, and service utilization is ongoing.
  • Initial feedback shows high PCP interest and engagement.
  • Qualitative assessments of program feasibility and acceptability are being conducted; adoption by UKHS Family Medicine is planned for mid-2025.

Conclusions:

  • The implemented model empowers PCPs with decision support, biomarkers, and collaborative pathways to enhance diagnostic accuracy and access to care.
  • This approach bridges primary and specialty memory care, offering a scalable solution for rising dementia care demands and specialist shortages.