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Clinical Manifestations.

Danilo Barroso de Sousa1, Cecilia Patricia Popolin1, Lucas Pelegrini Nogueira de Carvalho1

  • 1Federal University of São Carlos, São Carlos, São Paulo, Brazil.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 24, 2025
PubMed
Summary
This summary is machine-generated.

Higher anxiety symptoms are linked to poorer cognitive performance in older adults. Addressing anxiety may improve cognitive health and quality of life in later years.

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Area of Science:

  • Gerontology
  • Neuroscience
  • Psychiatry

Background:

  • Anxiety and neurocognitive disorders are prevalent in older adults.
  • Anxiety is known to disrupt cognitive functions.

Purpose of the Study:

  • To investigate the association between anxiety symptoms and cognitive performance in Brazilian older adults.
  • To determine if anxiety independently impacts cognitive function in this population.

Main Methods:

  • Cross-sectional study of 102 community-dwelling older adults (aged 60+).
  • Cognitive performance assessed using the Addenbrooke's Cognitive Examination Revised (ACE-R).
  • Anxiety symptoms measured by the Geriatric Anxiety Inventory (GAI); robust linear regression used for analysis.

Main Results:

  • Higher anxiety symptom scores (GAI) were significantly associated with poorer cognitive performance (ACE-R).
  • Age and educational achievement also showed significant associations with cognitive scores.
  • Sex, living arrangements, income, and household size did not show significant associations.

Conclusions:

  • Increased anxiety symptoms are independently linked to cognitive difficulties in older adults.
  • Managing anxiety is crucial for preserving cognitive function and enhancing quality of life in aging populations.