Efficacy of flower pollen extract with vitamins in improving urinary and sexual function in patients with chronic...

To assess the efficacy and safety of Flower Pollen Extract with Vitamins (PEV) in improving urinary and sexual function in men diagnosed with chronic prostatitis (CP).

A retrospective controlled study was conducted involving 145 men with CP. Participants were divided into two groups: the intervention group received PEV (n=71) and the control group received ibuprofen (n=74). Clinical and functional outcomes were evaluated at baseline and at 1, 3, and 12 months post-treatment.

Both groups exhibited comparable baseline characteristics. At 3 months, the PEV group demonstrated significantly greater improvement in IPSS (9.4 ± 2.7 vs. 10.3 ± 2.6, p=0.04), NIH-CPSI (11.5 ± 3.7 vs. 13.6 ± 4.2, p=0.002), and IIEF-5 (19.8 ± 3.6 vs. 17.7 ± 3.3, p<0.001). These benefits were maintained and further enhanced at 12 months, with mean IPSS 7.6 ± 2.1, NIH-CPSI 6.5 ± 2.4, and IIEF-5 21.6 ± 3.3 in the PEV group (all p<0.005). No significant differences were observed in Qmax.

Long-term PEV therapy significantly improves urinary and sexual function in men with CP compared with ibuprofen treatment, demonstrating sustained, time-dependent efficacy and excellent safety.