Related Experiment Video
Updated: Jan 7, 2026

12:42
Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
Published on: January 7, 2019
10.1K
[Measles: An Old-New Disease].
Esther Aronson1, Dror Iakir2, Snir Yehezkeli2
1Epidemiology Division, Israeli Ministry of Health, Israel.
Harefuah
|December 25, 2025
Summary
Measles outbreaks are rising globally, threatening elimination status even in developed nations like Israel. This review examines measles, its vaccine, and strategies to prevent future outbreaks and maintain elimination.
Area of Science:
- Public Health
- Infectious Diseases
- Vaccinology
Background:
- Measles (Rubeola) is a highly contagious disease with significant historical global morbidity and mortality.
- Vaccination has drastically reduced measles incidence, yet recent years show a concerning increase in outbreaks worldwide.
- Developed countries, including Israel, face a renewed risk of measles endemicity.
Purpose of the Study:
- To review the epidemiology of measles and its vaccine.
- To analyze the re-emergence of measles in Israel and globally over the past decade.
- To discuss preventive strategies for future outbreaks and maintaining measles elimination.
Main Methods:
- Literature review of measles epidemiology and vaccination.
- Analysis of recent measles outbreak data in Israel and worldwide.
- Discussion of public health interventions and policy recommendations.
Main Results:
- Despite high vaccination rates, measles outbreaks have resurged globally in the last decade.
- Israel, like other developed nations, is at risk of losing its measles elimination status.
- Specific preventive measures are crucial to control transmission and prevent endemicity.
Conclusions:
- Sustained high vaccination coverage is essential for measles control.
- Enhanced surveillance and rapid response are critical to manage outbreaks.
- Maintaining measles elimination requires a concerted global and national effort, including robust public health strategies.
More Related Videos
Related Concept Videos
Vaccinations
51.1K
Overview
51.1K
Viral Recombination
24.8K
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
24.8K
Microorganisms in Medicine and Therapeutics
911
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
911
Viral Mutations
39.5K
A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
39.5K
Immunological Memory
14.9K
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
14.9K
Cross-reactivity
32.8K
Overview
32.8K

