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Clinical Manifestations.

Bin Huang1, Duong Huynh1, Mary Patterson1

  • 1BrainCheck Inc., Austin, TX, USA.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 25, 2025
PubMed
Summary

A new Chinese version of the BrainCheck Assess (BC-Assess) digital cognitive test was developed for older Chinese-Americans. This pilot study found the translated assessment highly usable, though some cultural adaptations are still needed.

Area of Science:

  • Gerontology
  • Neuroscience
  • Health Informatics

Background:

  • Chinese-Americans are a rapidly growing demographic in the US, with a significant portion aged 65+.
  • Many older Chinese-Americans are first-generation immigrants with limited English proficiency, hindering access to standard cognitive tests.
  • There is a critical need for linguistically and culturally appropriate cognitive assessments for this population.

Purpose of the Study:

  • To translate the BrainCheck Assess (BC-Assess) digital cognitive assessment battery into Simplified Chinese (C-BC-Assess).
  • To evaluate the usability and identify necessary cultural adaptations of the C-BC-Assess through a cognitive interview study with older Chinese adults.

Main Methods:

  • Independent translation of BC-Assess into Simplified Chinese by two bilingual experts.

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  • Usability testing of C-BC-Assess with five healthy older Chinese adults using an iPad.
  • Application of the "think-aloud" method during testing to capture real-time feedback.
  • Post-test interviews to gather participants' overall experiences and suggestions.

    • Main Results:

    • All five participants, aged 60-73 with college or graduate degrees, rated C-BC-Assess highly for usability (average score 1.6/5).
    • Participants, including those more familiar with Traditional Chinese, reported no difficulties with the Simplified Chinese version.
    • Minor areas requiring further cultural adaptation in instructions and assessments were identified.

    Conclusions:

    • The development of a Chinese version of BC-Assess is feasible, building upon the existing English platform.
    • The study confirmed the high usability of the translated cognitive assessment.
    • Further cultural adaptations beyond direct translation are necessary to optimize relevance and user experience for older Chinese-Americans.