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Clinical Manifestations.

Rafi Haddad1,2, Elena Tsoy3, Judith Aharon-Peretz2,4

  • 1Global Brain Health Institute, University of California, San Francisco, San Francisco, CA, USA.

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Summary
This summary is machine-generated.

The Tablet-based Cognitive Assessment Tool Brain Health Assessment (TabCAT-BHA) effectively identifies cognitive impairment in Arabic-speaking Israelis. This culturally adapted tool shows high accuracy, aiding in early detection and addressing healthcare disparities.

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Area of Science:

  • Neurology
  • Gerontology
  • Public Health

Background:

  • Dementia presents a significant public health challenge in the Middle East and North Africa, particularly impacting Arabic-speaking populations.
  • Cognitive healthcare disparities exist for Arabic-speaking individuals in Israel due to a lack of culturally and linguistically adapted assessments.
  • Brief, non-language-dependent cognitive measures are needed to bridge this gap.

Purpose of the Study:

  • To evaluate the concurrent validity and discrimination accuracy of the Arabic version of the Tablet-based Cognitive Assessment Tool Brain Health Assessment (TabCAT-BHA).
  • To assess the TabCAT-BHA's utility in detecting cognitive impairment among Arabic-speaking older adults in Israel.

Main Methods:

  • 57 older adults with cognitive impairment (MCI or dementia) and 39 cognitively normal individuals completed the Arabic TabCAT-BHA.
  • Cognitively impaired participants also completed standard paper-and-pencil tests for verbal memory, visual memory, visuospatial skills, and processing speed.
  • Logistic regressions, ROC curves, and Pearson's correlations were used to assess discrimination accuracy and concurrent validity, adjusting for age, sex, and education.

Main Results:

  • The TabCAT-BHA demonstrated excellent discrimination accuracy (AUC = 0.97, sensitivity = 0.93, specificity = 0.79) in detecting cognitive impairment.
  • Strong correlations were found between specific TabCAT-BHA subtests and corresponding standard cognitive tests (e.g., Birdwatch with visual memory, Favorites with verbal memory).
  • The Match subtest showed moderate associations with all examined cognitive domains, reflecting the role of executive functions.

Conclusions:

  • The Arabic TabCAT-BHA is a valid and efficient tool for identifying cognitive impairment in Arabic-speaking Israelis.
  • The findings support the use of TabCAT-BHA to address cognitive healthcare disparities in this population.
  • Future research will focus on refining norms and confirming its utility for early disease detection in Mild Cognitive Impairment.