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Clinical Profile of Pediatric Oncology Patients Treated by Radiotherapy: A Retrospective Audit from a Tertiary Cancer

Sanjay Kini B1, Aashish Papneja1, Vasudeva Bhat K2,3

  • 1Department of Community Medicine, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.

South Asian Journal of Cancer
|December 25, 2025
PubMed

Insights

This study highlights the crucial role of radiotherapy in treating pediatric cancers in South India. Radiotherapy is an integral part of multimodal cancer therapy for children, demonstrating its continued importance in patient treatment.

Area of Science:

  • Pediatric Oncology
  • Radiation Oncology
  • Cancer Epidemiology

Background:

  • Increasing incidence of pediatric cancers in India necessitates multimodal treatment approaches.
  • Radiotherapy is a key component of pediatric cancer therapy.
  • Limited data exists on the profile of pediatric cancer patients receiving radiotherapy in South India.

Purpose of the Study:

  • To describe the profile of pediatric cancer patients who underwent radiotherapy in South India.
  • To understand the sociodemographic and diagnostic characteristics of these patients.
  • To assess the treatment intent and outcomes in this population.

Main Methods:

  • A record-based retrospective study was conducted at a tertiary care hospital in South India.
  • Data abstraction form collected sociodemographic details, primary and confirmed diagnoses, radiotherapy site, and patient status.
  • Chi-square or Fisher's exact tests analyzed associations between patient status and influencing factors.

Main Results:

  • The largest proportion of cases (30.4%) were in the 10-14 years age group.
  • Hematolymphoid malignancies accounted for 48 cases, while solid tumors were diagnosed in 67 cases.
  • A significant majority (95.6%) of patients received radiotherapy with curative intent.

Conclusions:

  • Radiotherapy is an essential component of cancer-directed therapy for children.
  • The findings underscore the continued integral role of radiotherapy in pediatric cancer treatment within the studied population.
  • Further research can inform optimized radiotherapy strategies for pediatric cancer patients in the region.
Abstract

Keywords:
children with cancerclinical profilepediatric oncologyradiotherapytertiary cancer care center

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