Palpitation post-vaccination: What should we do?

Area of Science:

• Cardiology
• Immunology
• Public Health

Background:

• mRNA COVID-19 vaccines are widely administered.
• Adverse events, though rare, require thorough investigation.
• Myocardial inflammation post-vaccination is an emerging clinical concern.

Purpose of the Study:

• To report a case of suspected vaccine-related myocarditis.
• To discuss diagnostic challenges and management strategies.
• To emphasize the importance of a multidisciplinary approach.

Main Methods:

• Case report of a 37-year-old female presenting with acute symptoms post-vaccination.
• Utilized serial ECGs, blood tests (troponin-I, TFTs), and tilt table testing.
• Performed Cardiac MRI to assess for myocardial inflammation.

Main Results:

• Initial investigations including ECG, troponin-I, and thyroid function tests were normal.
• Tilt table test results were unremarkable.
• Cardiac MRI revealed myocardial edema and inflammation at the basal anteroseptal wall.

Conclusions:

• This case suggests a potential link between mRNA COVID-19 vaccination and myocardial inflammation.
• A high index of clinical suspicion is crucial for timely diagnosis.
• Multidisciplinary team involvement is essential for effective patient management.