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Chemically modified DNA aptamers and DNAzymes for expanded functional capabilities.

Canyu Zhang1, Ke-Siyi Ma1, Zifan Zhang1

  • 1Lab of Applied Biocatalysis, School of Food Science and Engineering, South China University of Technology Guangzhou 510640 Guangdong China yufeicao@scut.edu.cn.

Chemical Science
|December 25, 2025
PubMed
Summary

Chemically modifying DNA aptamers and DNAzymes enhances their stability and functionality. This review covers recent advances, challenges, and future directions for these versatile DNA molecules.

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