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Diagnosing Autism in Adults: Clinically Focused Recommendations
Antonio F Pagán1, Daniel D Flint2,3, Katherine A Loveland1
1UTHealth Houston.
Journal of Health Service Psychology
|December 25, 2025
Summary
Late diagnosis of autism spectrum disorder in adults can impact quality of life. This paper guides clinicians in assessing adults for autism, considering masking and co-occurring conditions, and tailoring treatments for better outcomes.
Area of Science:
- Neurodevelopmental disorders
- Clinical psychology
- Adult psychiatry
Background:
- Autism spectrum disorder (ASD) is often undiagnosed in childhood.
- Missed diagnoses in childhood are linked to co-occurring conditions and reduced adult quality of life.
- Adults may present with unique challenges in ASD assessment, including symptom masking and sex/gender differences.
Purpose of the Study:
- To provide practicing clinicians with concise, up-to-date information for evaluating adults with potential autism spectrum disorder.
- To highlight key factors clinicians should consider during adult ASD assessments.
- To guide treatment providers in tailoring interventions for newly diagnosed autistic adults.
Main Methods:
- Review of current literature on adult autism spectrum disorder assessment.
- Consideration of factors specific to adult diagnosis, such as masking and sex/gender variations.
- Emphasis on utilizing multi-trait assessment methodologies.
Main Results:
- Adult autism assessment requires attention to "masking" of symptoms.
- Family reports of developmental history are valuable when available.
- Co-occurring mental health conditions are common and require management.
Conclusions:
- Early identification and diagnosis of autism spectrum disorder are crucial for improving adult outcomes.
- Clinicians should employ comprehensive assessment strategies for adults.
- Personalized psychoeducation and evidence-based treatments are essential for autistic adults, particularly those with co-occurring conditions.
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