Outcomes of Bilateral Implantation of a New Aspheric Hydrophobic Non-Diffractive Extended Depth of Focus IOL with a...

To evaluate binocular distance-target corrected (DC) near vision in patients having bilateral implantation of Clareon Vivity and Clareon Vivity Toric IOLs (Alcon Vision, LLC) targeted for mini-monovision, with the dominant eye set at emmetropia and the non-dominant eye at -0.50 D.

A prospective, unmasked single-armed observational study of 25 adult patients undergoing bilateral Clareon Vivity IOL with mini-monovision. Binocular uncorrected (U) and DC visual acuity (VA) at distance (6 m), intermediate (66 cm), and near (40 cm); mean refractive spherical equivalent (MRSE) for each eye and difference between contralateral eyes; binocular uncorrected reading performance using MNRead; and patient reported outcomes using the PRO Questionnaire (Research Insight, LLC) were collected at 3 months postoperatively. The primary outcome was proportion of subjects achieving DCNVA 20/32 or better.

Mean MRSE was -0.17 and -0.49 D for dominant and non-dominant eyes at 3 months. 88% of subjects met the primary endpoint of DCNVA ≥ 20/32. MNRead testing showed a mean reading acuity of 0.12 logMAR, critical print size of 0.31 logMAR, and maximum reading speed of 144.78 wpm. 87.5% of subjects had little to no visual disturbances. 66.7% of patients reported occasional to no use of reading glasses. 95.8% patients were satisfied with their vision after surgery.

Bilateral implantation of Clareon Vivity lenses with a mini-monovision approach achieved good visual performance with low levels of visual disturbances and a high level of patient satisfaction. The majority of subjects were spectacle independent and reading performance was near normal for their age without correction.